ea0041ep1 | Adrenal cortex (to include Cushing's) | ECE2016
Kang Hee Young
, Hwang Jeong Ung
, Lee Myoungho
, An Jin Yong
, Jeung Eui-Bae
Glucocorticoid, known as cortisol, is a steroid hormone essential to the maintenance of homeostasis, and is released in response to stress and low blood glucose concentration. It is converted from cortisone by 11β hydroxysteroid dehydrogenase type 1 (11β HSD1). The liver plays a major organ in metabolism, has numerous functions, mostly consists of hepatocytes, and is a principal target of cortisol. In murine model, it was observed that too much cortisol or overexpres...